However, side effects are generally mild and go away as the body adjusts to the medication. You should also look for supplements from reputable manufacturers. While taking Zetia, tell your doctor right away if you experience extreme muscle pain, muscle tenderness, or dark-colored urine. Taking Zetia with a statin may cause this side effect. Cholestyramine (Prevalite) is a drug used to treat high cholesterol. * Sex and gender exist on spectrums. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. Drugs in this class prevent your small intestine from absorbing cholesterol. unusual tiredness or weakness. During your Zetia treatment, consider keeping notes on any side effects youre having. Before taking Zetia, talk with your doctor and pharmacist. Clinical studies have shown Zetia to be effective for treating primary high cholesterol when used alone or with statin drugs. The causes of POTS are unknown, but the problem is thought to lie in the communication breakdown between the brain and the cardiovascular system. Talk with your doctor about birth control options that may be best for you. For primary high cholesterol, Zetia is FDA-approved for use in adults and children* to decrease levels of: For this purpose, Zetia is used with a low-cholesterol diet. If youve noticed memory problems while taking Zetia, talk with your doctor. Learn about the side effects it can cause and how to manage them. For example, in studies, some people had to stop taking the drug because their liver enzyme levels increased. Some people with POTS also may have one or more . Both drugs are typically taken once each day. What is considered high cholesterol? Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. diarrhea. Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. Talk with your doctor about your health history before you take Zetia. shortness of breath or troubled breathing. Its intestinal molecular target is the Niemann-Pick C1-Like 1 (NPC1L1) sterol transporter. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Based on animal studies, Zetia may cause harm to the fetus when taken by a pregnant woman. Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by lightheadedness or dizziness when standing and a racing heart. The generic form of Zetia costs about the same as the generic form of Lipitor. Zetia is approved to treat certain forms of high cholesterol in adults when used with a low-cholesterol diet. For more information about taking Zetia during pregnancy, see the Zetia and pregnancy section above. In the video she posted on Thursday, the "Real Housewives of New York City" alum detailed her suffering from a severe dehydration issue and shared that her doctor . Zetia can interact with several other medications. Other drugs are available that can treat your conditions. For this purpose, Zetia may be used: The only FDA-approved dosage of Zetia is 10 mg once a day. You can use the study as a second opinion to make health care decisions. And generics tend to cost less than brand-name drugs. The cause of the disorder is unknown. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. It can develop suddenly or gradually over time. Other interactions can increase side effects or make them more severe. The brand name for this drug combination is Vytorin. Medications in the fibrate drug class are used to treat high cholesterol. When this happens, more cholesterol can then be cleared from your blood by your liver. If your muscle-related side effects dont go away or become severe, tell your doctor right away. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. No, clinical studies havent shown Zetia to affect blood pressure. Zetia contains the active drug ezetimibe. Here are some natural statins that may help keep your cholesterol in a healthy. These lists dont include all possible side effects. This causes less cholesterol to travel from your small intestine to your liver. muscle pain while taking ezetimibe with a statin. If you miss a dose of Zetia, you can take your missed dose as soon as you remember. High cholesterol may be caused by genetics, smoking, low amounts of physical activity, or eating too many high-cholesterol foods. Twelve weeks of treatment with Zetia and atorvastatin or simvastatin was compared with atorvastatin or simvastatin used alone. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Specifically, Zetia is used along with a low-cholesterol diet to treat: Zetia is approved to treat these conditions in certain situations. Such an increase in heart rate may mean that your . If you drink alcohol and have questions about drinking it during Zetia treatment, talk with your doctor. In clinical studies that lasted 8 weeks, Zetia was compared with a placebo (a treatment with no active drug). If you have questions about the differences between Zetia and statin drugs, talk with your doctor. Therefore, you shouldnt breastfeed if youre taking Zetia with a statin drug. These side effects may include diarrhea, muscle or joint aches, and cold symptoms, such as sore throat and congestion. For instance, some interactions can interfere with how well a drug works. You should always consult your doctor or another healthcare professional before taking any medication. Muscle-related problems are a possible side effect of Zetia when used with other medications. If your doctor confirms you had a mild allergic reaction to Zetia, theyll decide if you should continue using it. To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). Talk with your doctor about the risks of taking Zetia with warfarin. Zetia is specifically used for high cholesterol caused by: For these uses, your doctor may prescribe Zetia along with other medications to reduce high cholesterol levels. You may also have muscle cramps, spasms, or stiffness. Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health . Zetia may not be right for you if you have certain medical conditions or other factors that affect your health. Read more about how inherited high cholesterol affects life expectancy and what makes it different from regular hypercholesterolemia. Heres some detail on certain side effects this drug may or may not cause. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . Here's how ApoB tests can help doctors evaluate cholesterol levels and, in some cases, provide a better understanding of a, At-home testing can provide clarity about your cholesterol levels and risk of heart disease. If any of the following factors or conditions apply, you may have a higher risk of developing these muscle problems: If you have muscle-related side effects during Zetia treatment, talk with your doctor. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Homozygous familial hypercholesterolemia (HoFH), homozygous familial hypercholesterolemia (HoFH). Read more about these alternatives to traditional statin, Having high cholesterol puts you at risk for a heart attack or stroke. Your doctor may do liver function tests before you start treatment and regularly during your Zetia treatment. POTS-related fatigue is physical in nature . Your doctor might suggest one or more of these: fludrocortisone (helps the kidneys retain sodium) midodrine (causes the blood vessels to tighten) beta blockers (slow down the heart rate). Your doctor will determine the best dosage to fit your needs. As with all medications, the cost of Zetia can vary. They may want to select a different treatment option for you. Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. However, you may still experience muscle problems if you use Zetia alone. shaking and sweating. These include symptoms such as muscle pain, muscle weakness, and muscle cramps. stuffy nose. Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. However, it isnt known how Zetia may affect these risks. Drugs in this class prevent your small intestine from absorbing cholesterol. Yes, treatment with Zetia should lower your triglycerides. If you have questions about weight changes while using Zetia, talk with your doctor. Some people experience mild side effects with Zetia. A malfunctioning ANS is sometimes called 'dysautonomia'. They can give you tips on how to deal with any side effects that may be bothersome. In these groups, joint pain occurred in: The length of time that adults and children experienced joint pain while taking Zetia in these clinical studies isnt known. MNT is the registered trade mark of Healthline Media. After first three days stopped it for two days. If youre experiencing hair loss while using Zetia, talk with your doctor. Zetia, Baclofen, and Xanax are not known to cause itching at all, but the Xanax can cause problems with memory which you do describe. Using Zetia for high cholesterol. Avoid eating foods high in fat or cholesterol, or Zetia will not be as effective. Zetia is a prescription drug used to treat certain types of high cholesterol. What causes POTS? Youll likely take it once a day. New evidence shows that the drug makers Merck and Schering-Plough have conducted several studies of their popular cholesterol medicine Zetia that raise questions about its risks to the liver, but . The absence of symptoms doesn't necessarily mean that the cause of POTS is gone as well. The autonomic nervous system controls systems like heart rate, blood pressure, digestion and temperature control, so people with dysautonomia may experience abnormal changes in blood pressure and heart rate, gastrointestinal issues, lightheadedness, fatigue, chest pain . The following lists contain some of the key side effects that may occur while taking Zetia. If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. (Mixed hyperlipidemia is also known as mixed high cholesterol.). If youre using Zetia while sexually active with a female who could become pregnant, talk with your doctor about your birth control needs. Energy Drinks, such as Red Bull, should be avoided in those with POTS. Side effects may be more likely in older adults. Zetia is sometimes used with medications in the statin drug class. As with most drugs, some people can have an allergic reaction after taking Zetia. Our website services, content, and products are for informational purposes only. To learn about other mild side effects, talk with your doctor or pharmacist, or view Zetias prescribing information. It can also interact with certain supplements as well as certain foods. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Its not clear if CoQ10 prevents muscle-related side effects when Zetia is taken with a statin, but it might help. A medication timer may be useful, too. For more information about the effectiveness of Zetia for lowering your triglycerides, see the Zetia uses section above. Zetia is also used to reduce blood levels of fats called plant sterols in people with homozygous sitosterolemia. Below are examples of these side effects. Clinical studies involved adults and children ages 10 years and older. But keep in mind that Zetia is used to reduce cholesterol levels in your blood. You can learn more about how we ensure our content is accurate and current by reading our. Theyll guide you on the safest treatment options for you. People with HoFH have high levels of LDL (bad) cholesterol. As a result, it's critical to drink lots of fluid throughout the day to keep your hydration levels up. Youll also need to check your insurance plan, as it may only cover one or the other. dark colored urine. Zetia isnt a statin drug. However, excessive alcohol use can damage your liver over time. In addition, Zetia may be used with fenofibrate to treat mixed hyperlipidemia. Side effects of Lipitor and Zetia that are similar include diarrhea and joint pain. And do not stop using Zetia unless your doctor recommends it. They can suggest ways to help relieve your side effects, or they may recommend a different treatment option for you. Zetia contains the active drug ezetimibe. Do my other medications increase my risk of side effects with Zetia? But in studies, some people had to stop taking the drug due to feeling dizzy. * To learn more about this side effect, see the Side effects explained section below. Zetia is available as a tablet that you take by mouth. Learn how we can help. If you have any questions about eating certain foods while taking Zetia, talk with your doctor. This may be caused by genetics, smoking, not getting enough physical activity, or eating too many foods that are high in cholesterol. POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms upon standing. Lipitor ( atorvastatin) and Zetia ( ezetimibe) are used to lower cholesterol levels in the blood. There are no known interactions between Zetia and alcohol. Zetia is a brand-name drug that contains the active drug ezetimibe. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). If youre concerned about joint pain while using Zetia, talk with your doctor. However, animal studies dont always predict what will happen in humans. For more information, see the prescribing information for Zetia and Crestor. In Zetia's clinical studies, these were some of the side effects that occurred more often: pain in the arms or legs. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. Total cholesterol is the overall amount of cholesterol found in your blood. Note: Zetia isnt approved to lower these types of cholesterol: Cholesterol is measured in several ways. Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Examples of other drugs that may be used to treat primary high cholesterol include: Examples of other drugs that may be used to treat mixed high cholesterol include: Examples of other drugs that may be used to treat homozygous familial hypercholesterolemia include: Examples of other drugs that may be used to treat homozygous sitosterolemia include: You may wonder how Zetia compares with other medications that are prescribed for similar uses. Memory loss isnt a side effect of Zetia. Is it harmful to take a coenzyme Q10 (CoQ10) supplement along with Zetia to help prevent muscle-related side effects? Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. Some people witness mild symptoms, some have a big impact on their lives due . Zetia comes as a tablet that you swallow. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. Theyll likely suggest changes to your treatment plan. Statin drugs may pass into breast milk. A decrease in the transport of intestinal cholesterol to the liver reduces stores of hepatic cholesterol. Over time, plant sterols can build up in your blood vessels and raise your risk of heart disease. You may not have any symptoms of gallstones unless they cause your gallbladder to swell. sinusitis. Zetia has been found in breast milk during animal studies. Nausea/Vomiting. diarrhea*. Dr. said Zetia was different and would not cause these side effects, so I agreed to try it. trouble in swallowing. Zetia is FDA-approved to treat certain types of high cholesterol in adults and in children when used with a low-cholesterol diet. (For more information on the specific conditions Zetia can treat, see the Zetia uses section.). For more information, see the How Zetia works section below. (Fenofibrate is a drug used to lower your triglyceride levels.). Many rare diseases have limited information. These symptoms could be life threatening and require immediate medical care. Symptoms: This section is currently in development. MS: Can the Mediterranean diet help preserve cognitive health? Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. If you think youve taken too much of this drug, call your doctor. If youre currently taking cyclosporine, talk with your doctor about whether its safe for you to take Zetia. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. But its not clear whether this side effect occurred in studies. It can be taken with or without fenofibrate in adults. * Zetia is also approved to treat these conditions in children ages 10 years and older. If youre pregnant or breastfeeding, or if youre planning to become pregnant or breastfeed, tell your doctor. A Mayo Clinic study published this month in Pacing and Electrophysiology (PACE), suggests that a class of medications more commonly prescribed for older adults is a strong first-line treatment for teenagers with a debilitating condition called postural orthostatic tachycardia syndrome, or POTS. Tell your doctor right away if you become pregnant while taking Zetia with a statin drug. You may also want to check out the online communities at Bezzy. Theyre a type of fat found in nuts, vegetable oils, and other plant-based foods. More research is needed to know for sure. Pots or postural tachycardia syndrome is, also known as postural orthostatic tachycardia syndrome, is a condition that affects the flow of blood in the heart and brain. Plant sterols are similar to cholesterol. tender, swollen glands in neck. Zetia can be used to treat high cholesterol or homozygous sitosterolemia (a condition that causes high fat levels) in certain people. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. Lipitor is an HMG-CoA reductase inhibitor (a "statin" drug) and Zetia is a cholesterol -lowering drug. Most of these side effects may go away within a few days or a couple of weeks. You can take Zetia with or without food. Crestor is part of the statin drug class. Zetias mechanism of action is considered complementary to that of statins and fenofibrate. POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. I am a stay at home mama to a sweet baby girl, and wife to an amazing h. Most of Zetias side effects should go away within a few days or weeks. These drugs havent been directly compared in clinical studies. In these studies, 12 weeks of treatment with Zetia and fenofibrate was compared with Zetia taken alone, fenofibrate taken alone, or a placebo (a treatment with no active drug). For this purpose, Zetia is used with a low-cholesterol diet and is taken with atorvastatin or simvastatin in adults and in children ages 10 years and older. Learn about side effects, costs. People with this condition have high levels of plant sterols. Your doctor will likely start you on the typical dosage approved to treat your condition. People who may be at higher risk of this side effect include those who: Tell your doctor if any of the above apply to you before starting Zetia treatment. For treatment of mixed hyperlipidemia, Zetia is indicated to reduce total cholesterol, LDL cholesterol, non-HDL cholesterol, and ApoB. Treatment is targeted at relieving low blood volume or regulating circulatory problems that may cause the disorder. They are caused by deficiencies in enzymes involved in the synthesis of heme. POTS is an unusual condition in which your heart rate speeds up by 30 or more beats per minute with little or no change in blood pressure. High cholesterol occurs when you have more cholesterol in your blood than your body needs. Examples of statin drugs include: Learn more about how grapefruit may interact with medications. Here we look at how Zetia and Crestor are alike and different. Ezetimibe may be used alone or with other drugs (such as "statins" or . This means you should avoid foods that are high in cholesterol and other types of fat. Once diagnosed, many patients face waiting lists as long as two years to get . They can both be taken with or without food. Zetia is meant to be used in combination with a diet thats low in saturated fat and cholesterol. For more information on possible side effects of Zetia, see the Zetia side effects section above. It can cause mild side effects and, less commonly, serious side effects. Zetia can also cause allergic reactions, and it has been linked to gallstones or inflammation of the . Statins are another type of medication used to lower cholesterol. As patients we need to be constantly wary because it is increasingly clear that the pharmas have abrogated their responsibility on our behalf. But over time, heavy alcohol use can damage your liver. Zetia can also be used with statin drugs in adults. These include: Note: For more information about the potential negative effects of Zetia, see the Zetia side effects section above. To reduce your symptoms in . However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. Zetia is approved to treat different types of high cholesterol. Your body uses cholesterol to make some vitamins, hormones, and fluids that help you digest food. Dr. John Szawaluk answered. It belongs to a class of drugs called cholesterol absorption inhibitors. The only FDA-approved dosage of Zetia for children is 10 mg once a day. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Lipitor is part of the statin drug class. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. If you have questions about using Zetia and cholestyramine together, talk with your doctor. Postural orthostatic tachycardia syndrome (POTS) is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. Some people may develop mild or serious side effects during Zetia treatment. Zetia is FDA-approved to treat mixed high cholesterol when used with fenofibrate. Note: Some of the drugs listed here are used off-label to treat these specific conditions. fainting (passing out) problems with thinking, memory and concentration - this combination of symptoms is often called 'brain fog'. Its FDA-approved to treat certain forms of high cholesterol in adults and in children ages 10 years and older. Zetia side effects. To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Your risk of developing serious side effects may increase if you take Zetia with other medications to treat high cholesterol, such as statin drugs. It also isnt known how many adults and children experienced joint pain in clinical studies of Zetia used to treat other conditions. Also tell them about any vitamins, herbs, and supplements you use. You may be able to find testimonials online from people who take Zetia. For more information on the possible side effects of Zetia, talk with your doctor or pharmacist. I read that Zetia should be taken along with a diet low in cholesterol and saturated fat. Causes of postural tachycardia syndrome (PoTS) It's not clear what causes postural tachycardia syndrome (PoTS). What Are the Injectable Alternatives to Statins? However, Zetia shouldnt be used with fibrate drugs other than fenofibrate. Phil Fischer, M.D., medical director of Mayo Clinic's children's hospital and a POTS specialist, led . Zetias side effects are usually mild, especially if youre taking Zetia alone. Side effects could occur in children who are breastfed by someone taking a statin drug. Cholesterol can also be found in foods such as eggs, cheese, and meat. Ezetimibe can cause the breakdown of muscle tissue . Cholesterol itself isnt a harmful substance. Porphyria patients are often overly sensitive to sunlight. Liver problems. In studies, muscle problems commonly occurred in adults and children who took Zetia with statin drugs. Crestor contains the active drug rosuvastatin. Cholesterol is a fatty substance found in the cells of your body. Clinical studies looked at Zetia for the treatment of primary hyperlipidemia in adults and in children ages 10 years and older. Inability to speak. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Noticed memory problems while taking Zetia, tell your doctor will determine the dosage! First three days stopped it for two days youve noticed memory problems while taking Zetia, tell your.! 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What will happen in humans birth control needs, smoking, low amounts of physical activity, eating!
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